Magnetocardiographic versus PET images in «difficult-to-diagnose» patients with CAD


Chaikovsky I., Primin M., Nedayvoda I., Budnik N.

Institute for Cybernetics of NAS of Ukraine, Kiev, Ukraine

Summary. Presented clinical cases show great potential of joint analysis of the electrical activity of the heart based on the MCG dats and perfusion images based on PET, particularly in difficult-to-diagnose cases, i. e. patients with non-informative results of routine tests. 3D reconstruction of the current density on the basis of the inverse problem solving is the most promising direction of magnetocardiographic data. analysis.

Key words: magnetocardiography, PET, inverse problem, CAD.


Worldwide, coronary artery disease (CAD) is becoming pandemic [1]. Mortality from CAD is predicted to reach 23.4 million in 2030. Now days, chronic CAD s estimated to affect 16.8 million people in the United States; and 2.65 million people in the UK. CAD was the single most frequent cause of death in USA and Western Europe (about 1 in every 5 deaths).The estimated direct and indirect economic cost of CAD in the United States for 2009 is $ 165.4 billion. Moreover, in the developing world, particularly in Ukraine, prevalence of CAD is even higher and there is the tendency tends to affect people at a younger age and thus could negatively affect the workforce and economic productivity. The morbidity, mortality, and socioeconomic importance of CAD make its diagnosis and management fundamental for all practicing physicians [2].

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