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Value of magnetocardiography in patients with acute non-Q myocardial infarction

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Chaikovsky I.1 , Stadnyuk L.2, Bilinsky E.2, Mjasnikov G.3, Kazmirchuk A.3, Budnik N.3

1Glushkov Institute for Cybernetics o NAS of Ukraine, Kiev, Ukraine

2Shupyk National Medical Academy of Postgraduate Education, Kiev, Ukraine

3Main Military Clinical Hospital of Ministry of Defence of Ukraine, Kiev, Ukraine

ABSTRACT

Objective. Diagnostics of non-Q myocardial infarction is one of the most difficult and, at the same time, important problems in modern cardiology. Magnetocardiography (MCG), owing to its high sensitivity towards electrophysiological disturbances in myocardium, should intro-duce a significant contribution to differential diagnostics of non-Q MI. The objective of present paper is to specify MCG possibilities in diagnostics of non-Q MI. Materials and methods. 9 patients with acute non-Q MI (mean age 56 1 , Levshova Z. + 2 years) were examined, 6 of whom had anterior MI (AMI) and 3 of whom had inferior MI (IMI). Two additional groups of patients were examined for comparison: a) 9 patients with acute Q-MI (mean age 58 + 4 years) showing clear clinical signs and doubt- less infarctional ECG-dynamics and b) 10 patients with verified chronic CAD without MI. The control group consisted of 15 healthy volunteers. MCG mapping was performed by means of a single-channel SQUID-magnetometer installed in an unshielded room. 2-D (magnetic field maps parameters) and 3-D equivalent dipole motion on depth during ventricular depolarization.

Results. Statistically significant differences between all groups examined based both on 2-D and 3-D quantitative criteria were demonstrated.

Conclusion. The offered set of criteria based both on analysis of magnetic field distribution maps and on solving the inverse problem exhibits high sensitivity and specificity.

Keywords: non-Q myocardial infarction (MI), magnetocardiography, magnetic field distribution maps, equivalent dipole.

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